By Dr. Irena Cosic (auth.)
ISBN-10: 3034874758
ISBN-13: 9783034874755
ISBN-10: 3034874774
ISBN-13: 9783034874779
Biological procedures in any dwelling organism are in keeping with selective interactions be tween specific biomolecules. ordinarily, those interactions contain and are pushed via proteins, that are the most conductors of any existence technique in the organism. The actual nature of those interactions continues to be no longer renowned. This e-book offers a completely new method of research of biomolecular in teractions, particularly protein-protein and protein-DNA interactions, in line with the idea that those interactions are electromagnetic in nature. This new ap proach is the foundation of the Resonant popularity version (RRM), which was once devel oped over the past 15 years. convinced periodicities in the distribution of energies of delocalised electrons alongside a protein molecule are the most important to the protein's organic functionality, i.e. inter motion with its objective. If protein conductivity have been brought, then fees mov ing during the protein spine may possibly produce electromagnetic irradiation or ab sorption with spectral features akin to strength distribution alongside the protein. The RRM is in a position to calculating those spectral features, which we hypothesized will be within the diversity of the infrared and visual mild. those features have been proven with frequency features acquired ex perimentally for definite light-induced organic processes.
Read or Download The Resonant Recognition Model of Macromolecular Bioactivity: Theory and Applications PDF
Similar theory books
Download e-book for kindle: Prediction Theory for Finite Populations by Heleno Bolfarine
Plenty of papers have seemed within the final two decades on estimating and predicting features of finite populations. This monograph is designed to offer this contemporary idea in a scientific and constant demeanour. The authors' strategy is that of superpopulation versions during which values of the inhabitants components are regarded as random variables having joint distributions.
Rosalie T. Ruegg, Harold E. Marshall (auth.)'s Building Economics: Theory and Practice PDF
We now not construct constructions like we used to nor can we pay for them within the similar manner. constructions this present day aren't any longer basically safeguard yet also are existence help structures, communique terminals, information production facilities, and masses extra. constructions are really dear instruments that needs to be continually adjusted to operate successfully.
- Money, Sound and Unsound
- Logistics and Supply Chain Innovation: Bridging the Gap between Theory and Practice
- Global theory of minimal surfaces. Proc. Clay Inst. 2001 Summer School
- Bifurcation and Chaos: Theory and Applications
Additional resources for The Resonant Recognition Model of Macromolecular Bioactivity: Theory and Applications
Sample text
This result indicates that the amino acid residues which characterise the hot spots are important for the formation of the biologically active molecular structure with the consequent appropriate physical field conditions around the active site [25, 311. To evaluate the generality of this concept. similar analyses were carried out with hemoglobins as another group of heme-containing proteins. In contrast to myoglobin, hemoglobin is made up of four polypeptide chains held together by noncovalent interactions.
475 204 green light abs. 355 191 red light abs. 346 197 hem. light abs. 023 295 purple light abs. 281 241 flavodoxin light abs. 344 189 growth f. 293 185 growth f. 242 200 chymotr. 236 200 40 3. The Physical Meaning of the RRM These results strongly support the idea that RRM characteristic frequencies represent specific electromagnetic field oscillations within the infrared and visible range which are crucial for protein activity and interactions. These results also reinforce linear correlation between the RRM frequency space and wavelengths of biologically effective light irradiation with a correlation coefficient of K = 20 I.
19 The Resonant Recognition Model of Macromolecular Bioactivity. I. 4 Multiple cross-spectral function of five functionally non-related proteins Human a hemoglobin, rat ~ fibroblast growth factor (FGF), human tumor necrosis factor (TN F), protein A and CD41ymphocyte membrane protein. The resulting spectrum does not show a definite prominent peak. between macromolecules. ), both should have the same characteristic frequency. This has been shown in a number of examples of protein-protein interactions, including interleukins and their receptors 124, 29], nerve growth factors (NGFs) and their receptors [26,46], and FGFs and their receptors 125,341.
The Resonant Recognition Model of Macromolecular Bioactivity: Theory and Applications by Dr. Irena Cosic (auth.)
by George
4.3