By E. A. J. F. Lakke (auth.)
ISBN-10: 3540618783
ISBN-13: 9783540618782
ISBN-10: 3642606016
ISBN-13: 9783642606014
The stories defined the following have been performed within the Neuroregulation crew on the division of body structure of the collage of Leiden. during the last decade this staff has, in shut collaboration with the departments of neurosurgery and urology of the tutorial health center of Leiden, studied improvement and regeneration of the spinal twine and its peripheral nerves either from a neuroanatomical and a scientific viewpoint. in this interval the improvement of brainstem projections to the spinal twine of the rat used to be studied with a retrograde tracing strategy. Horseradish peroxidase was once injected into the spinal twine of rat fetuses, either at diverse a long time, and at assorted degrees of the spinal wire. those reports aimed to find regularities within the habit of descending fiber platforms that may yield perception into the good judgment that the apprehensive approach needs to hire to constitution its connectional development in the course of improvement. Such perception may well then be utilized to enhance regeneration of the anxious system.
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Additional resources for The Projections to the Spinal Cord of the Rat During Development: A Timetable of Descent
Example text
Substance P-immunoreactive neurons first appear at E 14, enkephalinergic neurons at E 16 (Sakanaka et al. 1982; Senba et al. 1982b). Fibers from PCRt are present in the cervical cord at P2 (Leong et al. 1984b). 3 Nucleus Reticularis Pedunculopontinus Tegmentalis The pedunculopontine nucleus (PPTg) is located dorsolateral in the pontine and mesencephalic reticular field. PPT g extends from the rostral pole of PB to the caudal pole of substantia nigra and is found in close association with the lateral edge of the superior cerebellar peduncle (scp).
Fibers from EW descend through the ipsilateral dorsolateral funiculus and project, with an ipsilateral preponderance, to all levels of the spinal cord (Basbaum and Fields 1979; Leong et al. 1984a; Loewy et al. 1977; Saper et al. 1976). The rostral EW projects predominantly to the cervical spinal cord, while the caudal EW shows no preference 36 (Loewy et al. 1977). 1983). The neurons of EW are generated from E12 to E 15, with a peak on E13 (Altman and Bayer 1981). Fibers emerging from the EW first reach the lower thoracic spinal cord level at E 19 (Kudo et al.
1981). Catecholamine fluorescence of LC is intense during the first 2 weeks postnatally and then gradually decreases to adult levels, which are reached by P35 (Agrawal et al. 1966; Loizou and Salt 1970; Loizou 1969, 1972). Noradrenergic fibers are present in the upper thoracic cord at E17, the lumbar cord at E18, and the sacral cord at E19. Ingrowth into the ventral and dorsal horns occurs 1 and 3 days, respectively, after the arrival of noradrenergic fibers at the pertinent level of the cord (Nygren et al.
The Projections to the Spinal Cord of the Rat During Development: A Timetable of Descent by E. A. J. F. Lakke (auth.)
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