By International Agency for Research on Cancer Staff
ISBN-10: 9283212711
ISBN-13: 9789283212713
ISBN-10: 9283215710
ISBN-13: 9789283215714
Offers re-evaluations of the carcinogenic dangers to people posed through publicity to a couple 121 natural compounds, regularly commercial chemical compounds, chosen from one of the 834 brokers evaluated in volumes 1-70 of the IARC Monographs sequence. chemical compounds have been chosen for second look at the foundation of substantial new proof that would demand a transformation within the IARC category of carcinogenic risk.The reviews are offered in 3 components. half one offers complete checks of all proper information on experimental carcinogenesis and melanoma epidemiology for 4 chemical substances: acrylonitrile 1 3-butadiene, chloroprene, and dichloromethane. of those, 1 3-butadiene remained categorized as most likely carcinogenic to people, and dichloromethane remained categorised as probably carcinogenic to people. Acrylonitrile, formerly categorised as most likely carcinogenic to people, used to be reclassified as probably carcinogenic. For chloroprene, formerly judged now not classifiable, new epidemiological facts and new bioassays demonstrating carcinogenicity in rats and mice supported category as in all probability carcinogenic to humans.Part re-evaluates 30 compounds for which new epidemiological or experimental carcinogenicity info have been on hand and for which alterations in type have been expected. half 3 presents short updates for seventy six compounds and teams of compounds for which new facts used to be constrained to experimental carcinogenicity facts. As no new epidemiological proof was once to be had, and no reclassification was once expected, those monographs reproduce the former precis reviews and replace those with descriptions of latest info.
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Additional info for Re-evaluation of Some Organic Chemicals: Hydrazine and Hydrogen Peroxide
Example text
A growing specialty application for acrylonitrile is in the manufacture of carbon fibres. These are produced by pyrolysis of oriented polyacrylonitrile fibres and are used to reinforce composites for high-performance applications in the aircraft, defence and aerospace industries. Other minor specialty applications of acrylonitrile are in the production of fatty amines, ion exchange resins and fatty amine amides used in cosmetics, adhesives, corrosion inhibitors and water-treatment resins (Brazdil, 1991).
6 mg/m3] (n = 3).
5 mg/m3]. Cleaning reactors resulted in exposures of 19 ppm [41 mg/m3]. 2– 304 mg/m3] during two disconnections. 4 mg/m3] for 10 min. , 1977). , 1996). (c) Resin production Personal, full-shift exposures, as measured by the companies and the study investigators, in two resin plants in the United States have been reported (Table 3). , 1990b). The other facility made acrylonitrile–butadiene–styrene (ABS) and styrene–acrylonitrile (SAN) resins and dispersions (Bloom & Zey, 1990). 2 mg/m3]). 5 mg/m3].
Re-evaluation of Some Organic Chemicals: Hydrazine and Hydrogen Peroxide by International Agency for Research on Cancer Staff
by Joseph
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