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Making Sense of Life: Explaining Biological Development with by Evelyn Fox Keller PDF

By Evelyn Fox Keller

What do biologists wish? If, not like their opposite numbers in physics, biologists are in general cautious of a grand, overarching conception, at what varieties of rationalization do biologists goal? How can we be aware of once we have "made sense" of lifestyles? Such questions, Evelyn Fox Keller indicates, supply no basic solutions. motives within the organic sciences are usually provisional and partial, judged by means of standards as heterogeneous as their subject material. it truly is Keller's goal during this daring and difficult e-book to account for this epistemological diversity--particularly within the self-discipline of developmental biology.

particularly, Keller asks, what counts as an "explanation" of organic improvement in person organisms? Her inquiry levels from actual and mathematical types to extra known explanatory metaphors to the dramatic contributions of modern technological advancements, specifically in imaging, recombinant DNA, and laptop modeling and simulations.

A background of the varied and altering nature of organic clarification in a very charged box, Making experience of Life attracts our consciousness to the temporal, disciplinary, and cultural parts of what biologists suggest, and what they comprehend, after they suggest to provide an explanation for existence.
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Additional info for Making Sense of Life: Explaining Biological Development with Models, Metaphors, and Machines

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32 For the most part, English and American reviewers were noticeably more sympathetic, even if they were a bit uncertain as to whether this was biology or not. Bashford Dean, a biologist at Columbia University, reviewed the 1910 book for Science, and although he begins by suggesting that “analogy” would be a more appropriate word for the title of Leduc’s book than “theory,” he is inclined to give the author a great deal of credit, if only for reminding us of the still unsolved problem that lies at the foundation of biology.

Despite numerous successes in identifying the physical and chemical basis of vital phenomena, the processes that were then seen as most basic to organismic life—growth and reproduction, and perhaps especially morphogenesis and development—appeared totally resistant to physicalist explanation. Faced with this question, Leduc’s efforts were far from silly: while they may not have been useful in identifying the actual physical basis of such phenomena, at the very least they 48 l MAKING SENSE OF LIFE demonstrated that purely physical dynamics could, in principle, give rise to processes so similar as to void the most obvious complaint.

Furthermore, other questions—especially questions about the mechanism of heredity—had come to take center stage, and to these questions Leduc’s method could contribute nothing at all. One last point, and it is to note the frequency with which such descriptors as marvelous, wonderful, spectacular, strange, and amazing were employed by Leduc and his readers. Indeed, even Leduc’s detractors’ insistence that his creations bore no greater resemblance to actual organisms than that between “a live person and his marble image” summons forth, merely by the invocation of entrenched myths and literary motifs in which statues do come to life (or in which living beings are turned to stone), the very sense of wonder these critics wished to squelch.

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Making Sense of Life: Explaining Biological Development with Models, Metaphors, and Machines by Evelyn Fox Keller


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