By Henry C. Vogel, Celeste M. Todaro
ISBN-10: 1591243637
ISBN-13: 9781591243632
This is a well-rounded instruction manual of fermentation and biochemical engineering providing innovations for the industrial creation of chemical compounds and prescription drugs through fermentation. Emphasis is given to unit operations fermentation, separation, purification, and restoration. rules, approach layout, and gear are targeted. atmosphere points are covered.
The functional elements of improvement, layout, and operation are under pressure. conception is integrated to supply the required perception for a specific operation. difficulties addressed are the gathering of pilot information, number of scale-up parameters, choice of the appropriate piece of kit, pinpointing of most likely hassle spots, and techniques of troubleshooting.
The textual content, written from a realistic and working standpoint, will support improvement, layout, engineering and creation group of workers within the fermentation undefined. members have been chosen according to their business historical past and orientation. The ebook is illustrated with a number of figures, pictures and schematic diagrams.
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Additional resources for Fermentation and biochemical engineering handbook : principles, process design, and equipment
Sample text
11 sv I 81' P Dtmbrant - SV4 t i indicator I Mars s p a c t r a w t t r i W! MSP - 300 j Knockout p o t sv2 Drain c Bypass c Punp 0-100 Pump 0- , s 1 0v 0 II B Figure 9. Schematic representation of analytical system for outlet gas from fermenter. (SVJ solenoid valve; (NVJ needle valve; (Thy) thermistor. Fermentation Pilot Plant 19 As shown in the right side of Fig. 9, a quadrupole mass spectrometer, MSG 300, with a gas-tight ion source, secondary electron multiplier, direction detector, and a turbo-molecular pump (TURBOVAC 150) is equipped with a membrane inlet (all from Nippon Shinku, Tokyo).
With the cone for a continuous flow rate of perfusion, the flow rate in the column is inversely proportional to the square of the radius of the cone at any given position. If the ratio of the radii of the inlet and outlet is 1:10 and the flow rate of the outlet is 1/100 of the inlet flow rate, then the separation efficiency of the supernatant fluid and suspended cells are improved. As shown in Fig. 13, the jacket type sedimentary system allows easy control of the temperature for separating the static supernatant from the cells.
J. Cell. , 110:43 (1982) 53. , J. Biol. , 252558 (1977) 54. , Tissue Culture, 9:286 (1983) 5 5 . , In Vitro, 23:317 (1987) 56. Gladeen, M. , Trends in Biotechnology, 1:102 (1983) 57. Girard, H. , Develop. Biol.
Fermentation and biochemical engineering handbook : principles, process design, and equipment by Henry C. Vogel, Celeste M. Todaro
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