By Barry M. Brenner, Maarten W. Taal, Glenn M. Chertow, Philip A. Marsden, Karl Skorecki, Alan S. L. Yu
ISBN-10: 1416061932
ISBN-13: 9781416061939
The recent variation of this vintage source keeps to convey entire, authoritative assurance of each point of kidney improvement and serve as, pathophysiology, prognosis, and remedy of renal illnesses and stipulations. It's easily the source to show to for info on any point of the strong point. Now with much more sensible, clinically targeted info on new medicinal drugs, new treatments, and coverings, the seventh variation presents state-of-the-art advice on each point of the field.
• deals 11 new chapters: Vasoactive Peptides and the Kidney · Disturbances of Calcium, Magnesium, and Phosphate Metabolism · method of the sufferer with Renal disorder · Interpretation of Urine Electrolyte and Acid-Base Parameters · Hematologic effects of Renal sickness · Cardiovascular facets of Renal affliction · Neuropsychiatric features of Renal illness · Erythropoietin treatment in Renal ailment and Renal Failure · extensive Care Nephrology · Extracorporeal remedy of Poisoning · and Donor and Recipient matters in Renal Transplantation.
• Discusses the most well liked subject matters within the box, together with acid-base issues · antihypertensive medicinal drugs · erythropoietin remedy in renal illness and renal failure · prescribing medications in renal illness · extensive care nephrology · cardiovascular facets of renal affliction · hemodialysis · and renal osteodystrophies.
• comprises clean standpoint from over a hundred twenty five overseas contributors-25 new to this edition.
• offers a extra elementary layout that incorporates an up to date layout, with extra tables, packing containers and key references for even swifter entry to big medical details · over 30,000 streamlined and up to date references · and key papers highlighted during the text.
• an advantage CD-ROM that comprises all of the illustrations from the ebook to be used in powerpoint shows.
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Extra resources for Brenner and Rector's The Kidney (7th Edition)
Sample text
It consists of an initial convoluted portion, the pars convoluta, which is a direct continuation of the parietal epithelium of Bowman's capsule, and a straight portion, the pars recta, which is located in the medullary ray (see Fig. 1-5 ). [177] This segment is not normally present in the rat or human nephron. [3] The outside diameter Figure 1-19 Transmission electron micrograph of S1 segment of rat proximal tubule. The cells are characterized by a tall brush border, a prominent endocytic-lysosomal apparatus, and extensive invaginations of the basolateral plasma membrane.
148] Morphologic evidence suggests that the autonomic nervous system is involved in the regulation of the function of the juxtaglomerular apparatus. [149] Barajas and Müller,[150] studying the juxtaglomerular apparatus of the rat with serial-section techniques at the ultrastructural level, analyzed the frequency of contacts between axons and the various cellular components of the juxtaglomerular apparatus. Nerve endings, principally adrenergic in type, were observed to be in contact with approximately one third of the cells of the efferent arteriole and with somewhat less than one third of the cells of the afferent arteriole in the region of the juxtaglomerular apparatus.
151] Extensive studies by Kopp and DiBona[152] provided convincing evidence that renin secretion is modulated by renal sympathetic nerve activity, which is consistent with the existence of neuroeffector junctions on renin-positive granular cells of the juxtaglomerular apparatus. The juxtaglomerular apparatus represents a major structural component of the renin-angiotensin system. [157] This initiates the tubuloglomerular feedback response by which signals generated by acute changes in sodium chloride concentration are transferred via the macula densa cells to the glomerular arterioles to control the glomerular filtration rate.
Brenner and Rector's The Kidney (7th Edition) by Barry M. Brenner, Maarten W. Taal, Glenn M. Chertow, Philip A. Marsden, Karl Skorecki, Alan S. L. Yu
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