By Aziz Nather
ISBN-10: 9812560890
ISBN-13: 9789812560896
This publication offers the newest updates at the significant demanding situations of bridging huge bone defects, the place recommendations variety from autografts, “tissue engineered bone”, biomaterials (hydroxyapatite, polycaprolactone and 3rd iteration biomaterials) to prostheses. Emphasis has been made on bone tissue engineering, the present cutting-edge during this box, difficulties encountered with mobile tradition expertise, scaffolds and bone progress elements (including genomics) and using gene remedy for the appliance of bone progress elements. consciousness has additionally been given to using bone autografts. It additionally covers using biomaterials and prostheses as different concepts for reconstruction. medical functions, as well as the fundamental technology, also are incorporated during the discussions.
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Additional resources for Bone Grafts and Bone Substitutes: Basic Science and Clinical Applications
Sample text
The material property of a given tissue is independent of geometry, and it assumes that the composition of the material is homogeneous. However, in contrast to an engineering material like metals, plastics or composites, biological materials can alter its material properties as well as its shape and size given the appropriate stimuli thus making the study of its mechanical properties more challenging (Hayes, 1991; Tencer and 35 36 • Pereira BP & Thambyah A Table 1: Summary of Elastic Modulus (E) and Ultimate Strength (a) of various musculoskeletal tissues and some common implant materials.
Likewise, the old taboo of applying a cerclage wire and strangulating the periosteal blood supply to a bone no longer holds true since we now know there are numerous periosteal vessels supplying bone at multiple entry points instead of just one vessel supplying it through a single portal of entry. The epiphysis and metaphysis have separate circulations, divided by the growth plate. They unite at maturity. After maturity, the three sources of blood supply to the diaphysis are: • Nutrient artery • Metaphyseal arteries (proximal, distal) These arteries enter the metaphysis on all sides at ligamentous attachments.
Tonna EA and Cronkite EP (1961) Cellular response to fracture studied with tritiated thymidine, /. Bone Joint Surg. 43A:352-362. , London. Urist MR and McLean FC (1952) Osteogenetic potency and new bone formation by induction in transplants to the anterior chamber of the eye, /. Bone Joint Surg. 34A:443-^176. Wray JB (1964) Acute changes in femoral arterial blood flow after closed tibial fracture in dogs, J. Bone Joint Surg. 46A: 1262-1268. 1 General Properties of Bone The properties of bone can be considered from both the structural and physiological aspects (Hayes, 1991; Tencer and Johnson, 1994; Martin and Burr, 1989).
Bone Grafts and Bone Substitutes: Basic Science and Clinical Applications by Aziz Nather
by Donald
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